Anxiety disorders such as phobias and PTSD are fairly common problems in society. One of the prime causes of anxiety disorders is the inability to overcome the fear for certain contexts when they no longer apply. Attempts to facilitate this process of overcoming fear, therefore, has been the focus of recent efforts to treat anxiety disorders. These efforts have culminated in the discovery that certain opioid compounds, called delta opioid receptor (DOP) agonists, assist in masking fear memory. Consequently, DOP agonists have been at the center of clinical explorations in this area over the last decade.
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