Pilot program aims to improve reproducibility, utility, and ethics of biomedical research

Addressing the widespread concern over transparency and reproducibility in biomedical research, one of the largest institutions in German science has begun to provide a framework, interventions, and incentives for improving the quality and value of translational research. The program is described by its leader, Ulrich Dirnagl of Berlin Institute of Health (BIH), and colleagues in a new article publishing on February 11 in the open-access journal PLOS Biology.
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Combining viral genomics and public health data revealed new details about mumps outbreaks

In 2016 and 2017, a surge of mumps cases at Boston-area universities prompted researchers to study mumps virus transmission using genomic data, in collaboration with the Massachusetts Department of Public Health and local university health services. As the outbreaks unfolded, the teams analyzed mumps virus genomes collected from patients, revealing new links between cases that first appeared unrelated and other details about how the disease was spreading that weren’t apparent from the epidemiological investigation.
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