The hormone estrogen plays many critical roles in men and women, in both healthy tissues and in cancer. In breast and gynecologic cancers, estrogen sends signals to tumors instructing the cancer cells to grow out of control. In recent years, studies have shed light on the growth-promoting role of estrogen in breast cancer. In endometrial cancer, which arises in the lining of the uterus, estrogen is known to play a critical role in tumor development, yet many insights from how it affects breast cancer do not apply to endometrial cancer. New research, published today in the journal Cancer Research, outlines findings scientists hope will advance our understanding of endometrial cancer and lead to more effective treatments.
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Globally more than 36 million people are living with HIV (PLWH), and a third of them have elevated depressive symptoms. Most PLWH live in developing countries with limited access to mental health services due to HIV-related stigma and a shortage of mental health professionals. Widely accessible smart phones offer a promising intervention delivery mode to address this gap.
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Stress response is the body’s normal physiological reaction to a situation that it perceives as threatening. However, stress can also impact important aspects of thinking, including problem solving. Researchers from the University of Missouri School of Medicine and the MU Thompson Center for Autism and Neurodevelopmental Disorders have discovered a potential indicator of how stress affects the brain and alters its ability to problem solve. These findings could ultimately understand and optimize treatment for patients suffering from stress-related illnesses.
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Laws affecting the labeling, marketing and taxation of sugary soft drinks impact the behavior of both consumers and manufacturers, according to two studies published this week in PLOS Medicine.
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Researchers attempting to improve the treatment for methicillin-resistant Staphylococcus aureus (MRSA) blood infections have discovered the combination of two antibiotics was no better than one, and led to more adverse effects.
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Deaths from heroin overdoses also jumped, from just under 2,100 deaths in 2002 to more than 15,000 deaths in 2018, according to background information in the study.

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The Hong Kong Polytechnic University today announced the development of the world’s most comprehensive automated multiplex diagnostic system (the System) which includes a fully automated machine and a multiplex full-screening panel for the point-of-care genetic testing of respiratory infectious disease including the 2019-nCoV.
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A new study evaluated the feasibility and acceptability of using T’ai Chi to improve chronic low back pain in adults over 65 years of age compared to health education and usual care.
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BrainCool AB, a Swedish medical device innovator, and a world leader in medical cooling technology for therapeutic hypothermia (brain cooling) and oncology, is pleased to announce that it has completed patient recruitment in the Scandinavian multi-center pivotal trial of 180 patients to investigate the patented Cooral® System for prevention of Oral Mucositis, one of the most debilitating side-effects of both standard and high-dose chemotherapeutic oncology treatments.
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The field of heart failure in pediatric populations has recently initiated more registries and clinical trials. This age group has special concerns and particularities regarding their clinical picture and management. Therefore, multiple disciplines have been involved in the management of heart failure in this age group.
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