A team of researchers from Stanford University, the University of Cincinnati and Cincinnati Children’s Hospital Medical Center has found that people with peanut allergies have an abundance of allergy-causing immunoglobulin E antibodies (IgE) in their guts. In their paper published in the journal Science Immunology, the group describes sequencing antibody genes from B-lineage plasma cells collected from multiple body locations in people with peanut allergies and what they found. Duane Wesemann and Cathryn Nagler with Brigham and Women’s Hospital and Harvard Medical School and the University of Chicago, respectively, have published a Perspective piece on the work done by the team in the same journal issue.
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