Myocardial blood flow (MBF) and myocardial flow reserve (MFR) have been identified as accurate indicators for graft failure after cardiac transplantation, according to a new study published in The Journal of Nuclear Medicine. Utilizing positron emission tomography (PET) myocardial perfusion imaging to quantify MBF and MRF, researchers were able to successfully detect patients with cardiac allograft vasculopathy (CAV), the most serious condition facing transplant patients late after their surgery. In addition, researchers found that MFR had a significantly higher accuracy when predicting the overall prognosis for cardiac transplant patients.
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