In popular experience the story of how serotonin modulates the brain might seem simple: pop an antidepressant, serotonin levels go up, mood improves. But neuroscientists acknowledge how little they know about how the neurotransmitter affects circuits and behavior in the incredibly complex human brain. To reveal the basics of how serotonin really works, scientists at MIT’s Picower Institute for Learning and Memory, funded by a new $1.16 million, four-year grant from the National Institutes of Health, will employ a far simpler model: the nematode worm C. elegans..
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