A real-world study of over 600,000 adult participants without a history of depression has found that the stop-smoking medication varenicline (marketed as Chantix in the US and Champix elsewhere in the world) does not appear to be associated with an increased risk of cardiovascular or neuropsychiatric hospitalization compared with nicotine replacement therapy (NRT). These findings, published in the scientific journal Addiction, confirm those of earlier clinical trials, providing further evidence of the safety of varenicline as an aid to stop smoking.
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