Unraveling mechanisms of ventricular enlargement linked to schizophrenia

Enlarged cerebral ventricles are found in 80% of individuals with schizophrenia, yet the mechanisms that lead to ventricular enlargement are mostly unknown. Scientists at St. Jude Children’s Research Hospital have found that two microRNAs play a critical role in a mechanism that results in ventricular enlargement in a type of mouse model. The results were reported today in Nature Communications.
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