Tauopathies are a group of neurodegenerative diseases characterized by the accumulation of phospho-tau—in other words tau associated to phosphate groups. Globular Glial Tauopathy, as well as Alzheimer’s, are members of this large group. It is characterized by the accumulation of phospho-tau in neurons and by the formation of protein inclusions in glial cells astrocytes or oligodendrocytes. The majority of these kinds of tauopathies are spontaneous, but some of them are caused by specific mutations.
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