Preventing metastasis by stopping cancer cells from making fat

Olivier Feron, a researcher at the University of Louvain (UCLouvain) Institute of Experimental and Clinical Research, seeks to understand how metastases form from a tumor. He previously demonstrated that the most aggressive cancer cells use significant amounts of lipids as energy sources. Now, Prof. Feron has discovered that cancer cells store lipids in small intracellular vesicles called lipid droplets. Cancer cells loaded with lipids are more invasive and therefore more likely to form metastases. Prof. Feron and his team sought to identify the link between lipid storage and metastasization.
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