Antibodies play a crucial role in our immune system by linking antigen recognition with complement activation for attacking foreign cells. Using high-speed atomic force microscopy, collaborative groups, including researchers at National Institutes of Natural Sciences and Nagoya City University, have successfully visualized the dynamic process of antigen-mediated interplay between antibodies and a complement component on membranes. Their findings provide mechanistic insights into the molecular processes behind Guillain-Barré syndrome.
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