Stress with disrupted body clock increases risk of metabolic disease

Everyday stress coupled with disruptions to the body’s internal clock may increase the risks of developing metabolic disorders including obesity and type 2 diabetes, according to a study presented at the Society for Endocrinology annual conference in Brighton. These mouse data indicate that environmental stress coupled with alterations in normal body clock function can affect food intake, promote weight gain and have long-lasting effects on stress responses. This may help explain why shift-work, jet lag and chronic stress in people can lead to metabolic disorders, as well as highlight therapeutic targets to investigate for future treatment.
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