School children who experience racial discrimination show higher risk markers for later cardiometabolic disease, including diabetes, heart disease or stroke, according to new research from The Australian National University (ANU) and the Murdoch Children’s Research Institute (MCRI).
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Author conflicts of interest may influence cannabidiol conclusions
Most articles published between 2014 and 2019 discussing the characteristics, use, and therapeutic effect of cannabidiol (CBD) are supportive, with supportive conclusions in more studies with CBD-related industry funding, according to a research letter published online March 17 in the Annals of Internal Medicine.
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Finding the weak points of cancer cells
The key to effective cures for cancers is to find weak points of cancer cells that are not found in non-cancer cells. Researchers at the Tokyo Metropolitan Institute of Medical Science found that cancerous and non-cancerous cells depend on different factors for survival when their DNA replication is blocked. Drugs that inhibited the survival factor required by cancer cells would selectively make cancer cells more vulnerable to replication inhibition.
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Infectious disease experts explore feasibility of coronavirus mobile app for instant contact tracing
A team of medical research and bioethics experts at Oxford University are supporting several European governments to explore the feasibility of a coronavirus mobile app for instant contact tracing. If rapidly and widely deployed, the infectious disease experts believe such an app could significantly help to contain the spread of coronavirus.
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Protein controls fat metabolism
Many foods—whether it’s the mozzarella on your favorite pizza, the olive oil in salad dressing or hollandaise sauce during asparagus season—contain lots of fat. The fatty acids in these foods are among the essential nutrients that people need to survive. When someone eats more fatty acids than the body can immediately convert into energy, the extra amount is stored in tissues—often in the form of unwanted rolls of fat around the hips or stomach—and serves as a kind of reserve supply.
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A protein that controls inflammation
A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, and psoriasis. They discovered how the protein A20 prevents inflammation and autoimmunity, not through its enzymatic activities as has been proposed, but through a non-enzymatic mechanism. These findings open up new possibilities for the treatment of inflammatory diseases. The results of the study are published in the leading journal Nature Immunology.
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Life expectancy crisis in the USA: The opioid crisis is not the decisive factor
Life expectancy in the USA is no longer rising. This stagnation has long been largely attributed to increasing numbers of drug deaths due to the opioid crisis. But Mikko Myrskylä and colleagues have now shown that deaths due to cardiovascular diseases are in fact having a much larger impact on life expectancy.
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COVID-19: Canada’s response hits a turning point
COVID-19 is an emerging risk for which the consequences are still unknown. That the virus could have potentially catastrophic health and economic consequences means that we must adopt a precautionary approach. Thus far, public health officials have focused on learning about the virus and containing it as best as they can.
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Researchers elucidate new mechanism for controlling DNA methylation in cells
Why normal cells turn into cancer cells One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation.
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Antioxidant treatment in acute ischemic stroke could delay onset of clinically overt dementia
Currently we are facing a dementia epidemic, with estimations showing that by 2050 approximately 131 million people will be affected.
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