Finding the weak points of cancer cells

The key to effective cures for cancers is to find weak points of cancer cells that are not found in non-cancer cells. Researchers at the Tokyo Metropolitan Institute of Medical Science found that cancerous and non-cancerous cells depend on different factors for survival when their DNA replication is blocked. Drugs that inhibited the survival factor required by cancer cells would selectively make cancer cells more vulnerable to replication inhibition.
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Infectious disease experts explore feasibility of coronavirus mobile app for instant contact tracing

A team of medical research and bioethics experts at Oxford University are supporting several European governments to explore the feasibility of a coronavirus mobile app for instant contact tracing. If rapidly and widely deployed, the infectious disease experts believe such an app could significantly help to contain the spread of coronavirus.
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Protein controls fat metabolism

Many foods—whether it’s the mozzarella on your favorite pizza, the olive oil in salad dressing or hollandaise sauce during asparagus season—contain lots of fat. The fatty acids in these foods are among the essential nutrients that people need to survive. When someone eats more fatty acids than the body can immediately convert into energy, the extra amount is stored in tissues—often in the form of unwanted rolls of fat around the hips or stomach—and serves as a kind of reserve supply.
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A protein that controls inflammation

A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, and psoriasis. They discovered how the protein A20 prevents inflammation and autoimmunity, not through its enzymatic activities as has been proposed, but through a non-enzymatic mechanism. These findings open up new possibilities for the treatment of inflammatory diseases. The results of the study are published in the leading journal Nature Immunology.
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