Engineered botox is more potent and safer in mice

Botulinum toxin (BoNT) is used for a range of applications from treating chronic pain to reducing the appearance of wrinkles, but when injected it can diffuse into the surrounding tissue and give rise to adverse effects. A new study publishing March 17 in the open-access journal PLOS Biology by Linxiang Yin and Min Dong of Boston Children’s Hospital, USA and colleagues shows that a subtle modification of an FDA-approved form of BoNT enhances binding to the nerve cells and improves the drug’s potency and safety.
Read More

Study reveals that odor alters how memories are processed in the brain

We’ve all experienced the strange memory-jogging power of scents. Perhaps the aroma of fresh pine brings you back to your childhood Christmases, or your heart starts to race when you step into a doctor’s office and the sharp odor of disinfectant fills your nose. Now, researchers from Boston University’s Center for Systems Neuroscience reveal just how much power scents have in triggering the memory of past experiences—and the potential for odor to be used as a tool to treat memory-related mood disorders.
Read More