Researchers identify factors essential for chronic hepatitis B infection

Researchers at Princeton University have identified a set of human proteins that the hepatitis B virus (HBV) uses to establish itself permanently inside liver cells. The study, published in the journal Nature Microbiology, could suggest new directions for therapies to treat chronic HBV infection, a condition that increases the risk of developing liver cancer and is responsible for almost 900,000 deaths worldwide each year.
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Microscopic STAR particles offer new potential treatment for skin diseases

Skin diseases affect half of the world’s population, but many treatments are not effective, require frequent injections, or cause significant side effects. But what if there was a treatment that eliminated injections, reduced side effects, and increased drug effectiveness? A skin therapy with these properties may be on the horizon from Mark Prausnitz’s Drug Delivery Lab at the Georgia Institute of Technology.
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Method to predict critical circulatory failure

Patients in a hospital’s intensive care unit are kept under close observation: Clinicians continuously monitor their vital signs such as their pulse, blood pressure and blood oxygen saturation. This provides doctors and nurses with a wealth of data about the condition of their patients’ health. Nevertheless, using this information to predict how their condition will develop or to detect life-threatening changes far in advance is anything but easy.
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Providing contraceptive care in the pediatric emergency department

A new study found that two-thirds of female adolescents ages 16-21 seen in a pediatric Emergency Department (ED) were interested in discussing contraception, despite having a high rate of recent visits to a primary care provider. More than 22% indicated that they would be likely to start or change contraception during the ED visit. Is the ED a “Golden Opportunity” for contraceptive education and initiation, ask the authors of this study in Journal of Women’s Health.
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Mathematical model could lead to better treatment for diabetes

One promising new strategy to treat diabetes is to give patients insulin that circulates in their bloodstream, staying dormant until activated by rising blood sugar levels. However, no glucose-responsive insulins (GRIs) have been approved for human use, and the only candidate that entered the clinical trial stage was discontinued after it failed to show effectiveness in humans.
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