Glucose acts as a double edged sword on longevity factor SIRT1

Feeding and fasting cycles exert control over metabolism and energy utilization. Aberrations are known to cause metabolic diseases, liver dysfunctions and accelerated aging. Expression and activity of the anti-aging factor SIRT1 has long been known to be beneficial in mitigating diseases such as diabetes, cardiovascular dysfunctions, neurodegeneration, cancer and aging. Global efforts are underway to both uncover molecular mechanisms that affect feed-fast cycles and also to regulate the activity of the longevity factor SIRT1.
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First study identifies risk factors associated with death in adults hospitalised with new coronavirus disease in Wuhan

Being of an older age, showing signs of sepsis, and having blood clotting issues when admitted to hospital are key risk factors associated with higher risk of death from the new coronavirus (COVID-19), according to a new observational study of 191 patients with confirmed COVID-19 from two hospitals in Wuhan, China, published in The Lancet.
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