A Franco-German research team led by Prof. Michael Sieweke, from the Center for Regenerative Therapies TU Dresden (CRTD) and the Center of Immunology of Marseille Luminy (CNRS, INSERM, Aix-Marseille University), today uncovered a surprising property of blood stem cells: not only do they ensure the continuous renewal of blood cells and contribute to the immune response triggered by an infection, but they can also remember previous infectious encounters to drive a more rapid and more efficient immune response in the future. These findings should have a significant impact on future vaccination strategies and pave the way for new treatments of an underperforming or overreacting immune system. The results of this research are published in Cell Stem Cell on March 12, 2020.
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Whole genomes of coronavirus from UK patients sequenced by Sheffield scientists
Scientists at the University of Sheffield, in partnership with Sheffield Teaching Hospitals Virology team, have sequenced their first two genomes of the novel coronavirus (COVID-19), with samples collected from patients treated in the UK.
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Single-drug therapy can attack several cellular targets using different modes of action
Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action.
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NCAM2 protein plays a decisive role in the formation of structures for cognitive learning
The molecule NCAM2, a glycoprotein from the superfamily of immunoglobulins, is a vital factor in the formation of the cerebral cortex, neuronal morphogenesis and formation of neuronal circuits in the brain, according to new study published in the journal Cerebral Cortex. The deficit of NCAM2 causes an incorrect migration of neurons and alters the morphology, cytoskeleton and functionality of these cells in the central nervous system.
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Disaster expert outlines how first responders will tackle COVID-19
As the coronavirus pandemic continues to swell, first responders and emergency room personnel are squarely in the path of COVID-19. Against a backdrop of reports of tight supplies of personal protective equipment, the Gazette turned to Paul Biddinger, director of Massachusetts General Hospital’s Center for Disaster Medicine, vice chairman for emergency preparedness in MGH’s Emergency Medicine Department, and associate professor at Harvard Medical School, to describe the massive public health challenge facing police, fire, and emergency medical responders.
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Coronavirus: why the US is in a mess, and how to fix it
It’s always been a question of when, and not whether, humanity would face another challenge on the scale of the 1918 flu pandemic.
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Fitness trackers help people stay active, study finds
Physical activity programs like the 10,000-step phenomenon alert inactive people to become active and stay active, according to a recent study involving University of Alberta physical activity experts.
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When is surgery not safe for seniors?
Poor physical function, dementia and depression all raise seniors’ risk of death after a major operation and should be factored into their pre-surgery assessments, researchers say.
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EKF launches STAT-Site WB β-ketone and glucose whole blood analyzer in the U.S.
EKF Diagnostics, the global in-vitro diagnostics company, announces a new addition to its Diabetes Care portfolio in the U.S. The STAT-Site WB is a dual-use whole blood β-ketone and glucose meter for professional use in the management of diabetes.
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Enoki mushrooms from Korea linked to deadly U.S. Listeria outbreak
Enoki mushrooms from Korea are the likely cause of a deadly Listeria outbreak in the United States that has sickened 36 people in 17 states, the U.S. Centers for Disease Control and Prevention says.
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