Why sequencing the human genome failed to produce big breakthroughs in disease

An emergency room physician, initially unable to diagnose a disoriented patient, finds on the patient a wallet-sized card providing access to his genome, or all his DNA. The physician quickly searches the genome, diagnoses the problem and sends the patient off for a gene-therapy cure. That’s what a Pulitzer prize-winning journalist imagined 2020 would look like when she reported on the Human Genome Project back in 1996.
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The silent threat of the coronavirus: America’s dependence on Chinese pharmaceuticals

As the new coronavirus, called 2019-nCoV, spreads rapidly around the globe, the international community is scrambling to keep up. Scientists rush to develop a vaccine, policymakers debate the most effective containment methods, and health care systems strain to accommodate the growing number of sick and dying. Though it may sound like a scene from the 2011 movie “Contagion,” it is actually an unfolding reality.
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Less than a quarter of at-risk adolescent boys ever get tested for HIV

Less than one in four adolescent men who have sex with men (AMSM) ever get tested for HIV, research funded by the National Institute on Minority Health and Health Disparities (NIMHD), part of the National Institutes of Health, has reported. The study, led by Brian Mustanski, Ph.D., of Northwestern University, Chicago, IL, appeared today in the journal Pediatrics.
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Decreasing liver macrophages reduces inflammatory proteins in rats

Certain white blood cells, called macrophages, occur in higher numbers in older individuals and contribute to inflammation and oxidative stress that accelerate the aging process, according to a team of researchers. New findings suggest that macrophages can be altered to become less inflammatory, which may aid in improving the life span of aged individuals.
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