New cohort of iPSC lines will accelerate research into Huntington’s disease

The European Bank for induced Pluripotent Stem Cells (EBiSC) and CHDI Foundation have collaborated with Censo Biotechnologies to generate a cohort of 45 iPSC lines derived from Huntington’s disease gene-expansion carriers and associated controls. These new lines will be used to further investigate the mechanisms of HD progression and for the development of novel therapeutics and will be widely available to any interested researcher via the EBiSC catalog at cells.ebisc.org.
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New gene mutation associated with Fabry cardiomyopathy

The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study. The variant plays a role in lipid metabolism. According to the researchers, patients carrying the mutation and manifesting changes in the heart should initiate treatment to prevent the disease from progressing. The study, conducted at the University of Eastern Finland and Kuopio University Hospital, was published in the journal Heart.
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