Neurodevelopmental disorders, including schizophrenia and autism, likely result from complex interactions that modify the effects of individual genes. In a new study, researchers evaluated the effects of over 300 pairwise knockdowns—reducing the expression of two genes simultaneously—of the fruit fly versions of genes located in a region of human chromosome 3 that, when deleted, has been implicated in these disorders. These interactions suggest that the disorders have a complex causation involving many genes, rather than resulting from the effects of any individual gene. One gene in particular, NCBP2, appears to be a key modifier, influencing the impact of other genes in the deletion.
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In 1988, a 6.9 magnitude earthquake struck near the northern Armenian city of Spitak. The temblor destroyed cities and is estimated to have killed between 25,000 and 35,000 people, many of whom were schoolchildren.
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A Western Sydney University research paper has painted an inspiring picture of local General Practitioners (GPs) who, despite the heavy personal and financial toll, are deeply committed to serving their communities.
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Being in love. It can take the shape of a long-term intimate partnership, or become an obsessive source of emotional excitement and distraction. When does being in love become similar to addiction, and can you be addicted to it?
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Researchers investigating the drug prescription response to a “superbug” enzyme that renders bacteria resistant to antibiotics are available to discuss why such resistance is posing a growing risk during pandemics such as the current coronavirus.
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Researchers from the University of Illinois at Chicago have discovered that endothelial cells -; those that create the inner lining of blood vessels -; have unique genetic signatures based on their location in the body.
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Most clinical practice guidelines in the U.S. are created by medical specialty societies. While there is widespread awareness of the potential for intellectual and financial conflict of interest by individual panel members, there is little recognition of the potential for the processes used by guideline panels to create conflict of interest.
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Researchers at Ohio University have published a new study in collaboration with Ugandan scientists, cautioning that humans place endangered mountain gorillas at risk of disease transmission during tourism encounters.
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Fifty-three cancer researchers from eight different academic institutions around the country and their federal agency partners met in Chapel Hill on January 27 and 28 to launch the next five years of the Cancer Prevention and Control Research Network.
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Sex differences in airway size are not innate, but likely develop because of hormonal changes around puberty, reports a new study by the University of Waterloo.
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