Exploring why mindfulness meditation has positive mental health outcomes

Over the past few decades, mindfulness meditation has become increasingly popular, particularly as a tool to reduce stress or anxiety and gain a greater sense of wellbeing. While many empirical studies have confirmed that regular meditation, especially mindfulness meditation, can have beneficial effects on people’s mental health, so far very little is known about the mechanisms underpinning these effects.
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Intratumoral heterogeneity may be responsible for chemotherapy resistance in patients with small cell lung cancer

Small cell lung cancer (SCLC) accounts for 14% of all lung cancers and is often rapidly resistant to chemotherapy, resulting in poor clinical outcomes. Treatment has changed little for decades, but a study at The University of Texas MD Anderson Cancer Center found that chemotherapy results in increased heterogeneity within the tumor, leading to the evolution of multiple resistance mechanisms.
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Recommended diuretic causes more side effects than similar hypertension drug

Chlorthalidone, the guideline-recommended diuretic for lowering blood pressure, causes more serious side effects than hydrochlorothiazide, a similarly effective diuretic, according to a new study led by researchers at Columbia University Irving Medical Center. The findings, published in JAMA Internal Medicine, contrast with current treatment guidelines recommending chlorthalidone over hydrochlorothiazide.
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