How the brain and its arteries communicate to supply blood to areas of heightened neural activity

The brain is a ravenous organ. A three-pound adult human brain consumes about a fifth of the body’s energy, yet it cannot store energy on its own and requires constant nourishment from the cardiovascular system. The organ’s energy needs fluctuate greatly depending on neural activity, and sufficient blood must be delivered to the right place at precisely the right time to ensure healthy brain function.
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Machine learning identifies personalized brain networks in children

Machine learning is helping Penn Medicine researchers identify the size and shape of brain networks in individual children, which may be useful for understanding psychiatric disorders. In a new study published today in the journal Neuron, a multidisciplinary team showed how brain networks unique to each child can predict cognition. The study—which used machine learning techniques to analyze the functional magnetic resonance imaging (fMRI) scans of nearly 700 children, adolescents, and young adults—is the first to show that functional neuroanatomy can vary greatly among kids, and is refined during development.
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Diabetes patients who use online tools manage disease better

In a study published in JAMA Network Open today, Kaiser Permanente scientists report that diabetes patients who used the Kaiser Permanente patient portal and mobile phone app improved their diabetes management outcomes. The large study, involving more than 111,000 patients, was unique in assessing the relationship between the use of online tools and medication adherence and blood glucose levels.
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