New way to chart human genome with CRISPR/nanopore sequencing technique

In search of new ways to sequence human genomes and read critical alterations in DNA, researchers at Johns Hopkins Medicine say they have successfully used the gene cutting tool CRISPR to make cuts in DNA around lengthy tumor genes, which can be used to collect sequence information.
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Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused as a side-effect of radiation can have a contrary effect by promoting the survival of triple-negative breast cancer cells, according to research published online in the International Journal of Radiation Biology by Jennifer Sims-Mourtada, Ph.D., director of Translational Breast Cancer Research at ChristianaCare’s Helen F. Graham Cancer Center & Research Institute.
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Researchers explore whether plaque identifying toothpaste could prevent heart attack, stroke

For decades, researchers have suggested a link between oral health and inflammatory diseases affecting the entire body — in particular, heart attacks and strokes.
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New study shows vision rehab treatment effective for stroke and injury related blindness

Jose Romano, Chief of the Stroke Division at the University of Miami Miller School of Medicine, co-authored a recently published international study that shows that visual rehabilitation is effective for patients who have suffered vision loss related to stroke or traumatic brain injury.
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Immunotherapy combo effective for patients with high-grade neuroendocrine cancer

Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial.
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Electron microscopy allows scientists to understand the molecular trigger of allergic reactions

An international research team has been able to describe the overall structure of the antibody type IgE, which is the key molecule in allergic diseases. This is a scientific breakthrough which provides important insights into basic mechanisms of allergic reactions and may pave the way for more effective allergy medicine. The new research results have now been published in the scientific journal Allergy.
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‘Resetting’ immune cells improves traumatic brain injury recovery in mice

Targeting overactive immune cells and dampening their chronic neurotoxic effects may offer new therapeutic strategies for traumatic brain injury (TBI), according to new preclinical research in mice, which has been published today in the Journal of Neuroscience.
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Women’s wellness: Stay heart-healthy during breast cancer treatment

A diagnosis of breast cancer is never easy to hear. Thanks to early diagnosis and better treatments, more women are surviving the disease. Dr. Jordan Ray, a Mayo Clinic cardiologist, urges all cancer patients to also pay attention to their heart health during and after treatment.
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Mayo Clinic Minute: What’s a cardiac stress test?

Your heart provides blood to all parts of your body. In order to determine if it’s pumping properly, your health care provider may order a cardiac stress test. It makes the heart pump harder and faster, and can reveal potential problems with blood flow.
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By decoding the coronavirus genome, scientists seek the upper hand against COVID-19

The genetic code of the coronavirus that causes COVID-19 is only about 30,000 characters long, but what a story it tells.
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